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Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Frontiers of Medicine doi: 10.1007/s11684-023-1044-4

Abstract: The primary etiology may be attributed to cytokine storm, which is triggered by the excessive releaseThus, we review the history of cytokine storm and the process of targeting IL-6 signaling to elucidate

Keywords： SARS-CoV-2     COVID-19     cytokine storm     interleukin-6     tocilizumab    

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Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 139-145 doi: 10.1007/s11684-015-0377-z

Abstract: In summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance

Keywords： inflammation     obesity     cytokine     energy expenditure     insulin resistance    

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A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification

Yimin Zhang, Liang Yu, LingLing Tang, Mengfei Zhu, Yanqi Jin, Zhouhan Wang, Lanjuan Li

Engineering 2021, Volume 7, Issue 1,   Pages 11-13 doi: 10.1016/j.eng.2020.03.006

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The Dust Storm Phenomena in Ningxia and the Countermeasures

Gao Qingxia,Ren Zhenhai

Strategic Study of CAE 2002, Volume 4, Issue 2,   Pages 16-21

Abstract: observation data from meteorological stations of Ningxia region, the spatial distribution and trend of dust stormphenomena (include dust storm, blowing sand and floating sand) are analyzed.

Keywords： dust storm     preventing and controlling dust storm and desertification     countermeasures and suggestion     blowing    

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Integrating storm surge modeling with traffic data analysis to evaluate the effectiveness of hurricane

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 6,   Pages 1301-1316 doi: 10.1007/s11709-021-0765-1

Abstract: An integrated storm surge modeling and traffic analysis were conducted in this study to assess the effectivenessThe Advanced Circulation (ADCIRC) model was applied to simulate storm tides during the hurricane eventModel simulated storm tides and winds were used to estimate the area affected by Hurricane Irma.Only moderate storm tides (maximum about 2.5 m) and maximum wind speed about 115 mph were shown in bothStorm surges did not rise to the 100-year flood elevation level.

Keywords： storm surge modeling     traffic     evacuation     Hurricane Irma    

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The Scientific Foundation of Chinese Herbal Medicine against COVID-19 Perspective

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Engineering 2020, Volume 6, Issue 10,   Pages 1099-1107 doi: 10.1016/j.eng.2020.08.009

Abstract: starting with severe viral infection and suppression of the immune system and eventually progressing to cytokinestorm, multi-organ damage, and lung fibrosis, which is the cause of mortality.

Keywords： Coronavirus disease 2019     Severe acute respiratory syndrome coronavirus     Chinese herbal medicine     Antiviral     Cytokinestorm     Lung fibrosis    

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Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 242-254 doi: 10.1007/s11684-013-0256-4

Abstract:

Inflammation has been considered as one of the hallmarks of cancer, and chronic hepatitis is a major cause of liver cancer. This review will focus on the pathogenic role of inflammation in hepatocarcinogenesis and will discuss recent advances in understanding the chronic hepatitis-liver cancer link based on hot spots in liver cancer research, including cellular interaction, cytokines, microRNA and stem cells. All of these mechanisms should be taken into consideration because they are crucial for the development of more efficacious therapeutic strategies for preventing and treating human chronic hepatitis and hepatocellular carcinoma.

Keywords： hepatocellular carcinoma     hepatitis     cytokine     stem cell     miRNA    

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High-affinity T cell receptors redirect cytokine-activated T cells (CAT) to kill cancer cells

Synat Kang, Yanyan Li, Yifeng Bao, Yi Li

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 69-82 doi: 10.1007/s11684-018-0677-1

Abstract:

Cytokine-activated T cells (CATs) can be easily expanded and are widely applied to cancer immunotherapy

Keywords： cytokine-activated T cells     high-affinity T cell receptor     cancer immunotherapy     TCR-CAT    

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Molecular characterization of two suppressor of cytokine signaling 1 genes (

Xue XU,Jiannan ZHANG,Juan LI,Yajun WANG

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 1,   Pages 73-83 doi: 10.15302/J-FASE-2015044

Abstract: Suppressor of cytokine signaling 1 (SOCS1) protein can inhibit the signal transduction triggered by someTaken together, these data suggest that both cSOCS1a and cSOCS1b may function as negative regulators of cytokine

Keywords： chicken     SOCS1a     SOCS1b     growth hormone     prolactin    

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Numerical simulations of morphological changes in barrier islands induced by storm surges and waves using

Soumendra Nath KUIRY, Yan DING, Sam S Y WANG

Frontiers of Structural and Civil Engineering 2014, Volume 8, Issue 1,   Pages 57-68 doi: 10.1007/s11709-014-0235-0

Abstract: supercritical coastal flows and morphological changes in a tidal/coastal inlet and barrier islands due to stormBarrier island breaching, overflow and overwash due to severe storm attack are simulated and the predicted

Keywords： coastal inlet     coastal process modeling     supercritical flow     sediment transport     barrier islands    

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Critical flow-storm approach to total maximum daily load (TMDL) development: an analytical conceptual

Zhang Harry, Yu Shaw

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 3,   Pages 267-273 doi: 10.1007/s11783-008-0058-0

Abstract: A practical, event-based critical flow-storm (CFS) approach was developed to explicitly addresses thecritical condition as a combination of a low stream flow and a storm event of a selected magnitude,

Keywords： representative hydrologic     occurrence     simulation approach     scarcity     alternative    

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A Storm over Potential 5G Interference

Chris Palmer

Engineering 2019, Volume 5, Issue 5,   Pages 815-816 doi: 10.1016/j.eng.2019.08.007

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Management of cytokine release syndrome related to CAR-T cell therapy

Hongli Chen, Fangxia Wang, Pengyu Zhang, Yilin Zhang, Yinxia Chen, Xiaohu Fan, Xingmei Cao, Jie Liu, Yun Yang, Baiyan Wang, Bo Lei, Liufang Gu, Ju Bai, Lili Wei, Ruili Zhang, Qiuchuan Zhuang, Wanggang Zhang, Wanhong Zhao, Aili He

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 610-617 doi: 10.1007/s11684-019-0714-8

Abstract: Cytokine release syndrome (CRS) is one of the most clinically important and potentially life-threateningThis syndrome is a systemic immune storm that involves the mass cytokines releasing by activated immune

Keywords： chimeric antigen receptor T cell     cytokine release syndrome     tocilizumab    

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The Regional Characteristics of the Atmospheric Environment and the Impact of Dust-storm in Beijing

Ren Zhenhai,Gao Qingxian,Su Fuqing,Wang Yaoting,Zhang Zhigang,Yang Xinxing

Strategic Study of CAE 2003, Volume 5, Issue 2,   Pages 49-56

Abstract: in China were researched, and the inner source and outersource of the dust-storm in China were determinedThe especially strong dust-storm on March 22, 2002, was taken as an example, by which the distributionof the original sources of the dust-storm was resolved, and the lots of the bare lands in Spring inThe initial process of the dust-storm appeared as a group of point sources, which were then combinedFinally, the dust-storm pollution of the large areas would appeare.

Keywords： dust-storm     transport passageway     environment pollution     China    

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Construction and Issues Related to the First Phase Project of Dust-storm Monitoring, Predicting and Service

Wang Xuechen,Cheng Lei

Strategic Study of CAE 2004, Volume 6, Issue 3,   Pages 64-67

Abstract:

Dust-storm is a kind of severe weather, which has comprehensive and significant impacts on socioeconomicEnhancing the abilities of dust-storm monitoring, predicting and service will be of great benefit toAt present, the comprehensive operation on dust-storm monitoring, predicting and service is still inThe implementing of the first phase project of dust-storm monitoring, predicting and service system will

Keywords： dust-storm     monitoring and predicting and service system     project construction     issues of extensive ability    

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Title Author Date Type Operation

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Journal Article

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Journal Article

A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification

Yimin Zhang, Liang Yu, LingLing Tang, Mengfei Zhu, Yanqi Jin, Zhouhan Wang, Lanjuan Li

Journal Article

The Dust Storm Phenomena in Ningxia and the Countermeasures

Gao Qingxia,Ren Zhenhai

Journal Article

Integrating storm surge modeling with traffic data analysis to evaluate the effectiveness of hurricane

Journal Article

The Scientific Foundation of Chinese Herbal Medicine against COVID-19

Elaine Lai-Han Leung, Hu-Dan Pan, Yu-Feng Huang, Xing-Xing Fan, Wan-Ying Wang, Fang He, Jun Cai, Hua Zhou, Liang Liu

Journal Article

Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Journal Article

High-affinity T cell receptors redirect cytokine-activated T cells (CAT) to kill cancer cells

Synat Kang, Yanyan Li, Yifeng Bao, Yi Li

Journal Article

Molecular characterization of two suppressor of cytokine signaling 1 genes (

Xue XU,Jiannan ZHANG,Juan LI,Yajun WANG

Journal Article

Numerical simulations of morphological changes in barrier islands induced by storm surges and waves using

Soumendra Nath KUIRY, Yan DING, Sam S Y WANG

Journal Article

Critical flow-storm approach to total maximum daily load (TMDL) development: an analytical conceptual

Zhang Harry, Yu Shaw

Journal Article

A Storm over Potential 5G Interference

Chris Palmer

Journal Article

Management of cytokine release syndrome related to CAR-T cell therapy

Hongli Chen, Fangxia Wang, Pengyu Zhang, Yilin Zhang, Yinxia Chen, Xiaohu Fan, Xingmei Cao, Jie Liu, Yun Yang, Baiyan Wang, Bo Lei, Liufang Gu, Ju Bai, Lili Wei, Ruili Zhang, Qiuchuan Zhuang, Wanggang Zhang, Wanhong Zhao, Aili He

Journal Article

The Regional Characteristics of the Atmospheric Environment and the Impact of Dust-storm in Beijing

Ren Zhenhai,Gao Qingxian,Su Fuqing,Wang Yaoting,Zhang Zhigang,Yang Xinxing

Journal Article

Construction and Issues Related to the First Phase Project of Dust-storm Monitoring, Predicting and Service

Wang Xuechen,Cheng Lei

Journal Article